Sotax – AT Manual / Semi-automated Dissolution System
The new state-of-the-art standard: Xtend™ Dissolution Line – modular, scalable, future-proof Fulfills all Pharmacopeia requirements for USP 1,2,5,6 dissolution methods Innovative circular bath design for perfect visibility AutoCompliance™ by design Large touch screen, 100 methods storage, users rights, USB and LAN interface
The new state-of-the-art standard: Xtend™ Dissolution Line – modular, scalable, future-proof
Fulfills all Pharmacopeia requirements for USP 1,2,5,6 dissolution methods
Innovative circular bath design for perfect visibility
AutoCompliance™ by design
Large touch screen, 100 methods storage, users rights, USB and LAN interface
Precise temperature control and easy handling & cleaning
The innovative circular design of the dissolution bath sets new standards for precise, quick and easy operation. Like its predecessor models, the AT dissolution bath has been optimized for ideal water circulation to ensure extremely high temperature homogeneity during the test. From fast filling and draining of the water bath with quick-connector, self-priming circulation pump, to motorized lift function, all handling and cleaning processes of the AT have been optimized for simple and fast execution. When adding test medium or removing vessels, the vertically lifted shaft drive provides excellent accessibility during all change-over and cleaning processes.
Flexibility maximized – suited for all dosage forms
Large inlet dimensions provide for a wide variety of tablet and sinker types to be introduced manually or automatically.
From standard tablets to capsules with large sinkers – the dissolution bath is capable of handling virtually all dosage forms.
Samples are protected from media before test start. As the inlets are closed during the test, media evaporation is prevented.
Flexibility maximized – various vessel styles
For full flexibility, the dissolution apparatus can be operated with various vessel types. The bath accommodates a broad variety of different vessel styles – from certified standard glass vessels to polycarbonate or low actinic glass vessels, 1 or 2 liter vessels, mini vessels, immersion cell vessel, peak vessels, and China vessels.
Flexibility maximized – USP 1,2,5,6 methods and more
Developed for USP 1,2,5,6 methods, the dissolution apparatus allows testing with different compliant and also non-compliant stirrer designs: Basket, Paddle, Paddle over disk, Rotating Cylinder, Extraction Cell, Mini Paddle, China Paddle, Stationary Basket, Intrinsic Dissolution. All parts are made of high quality material, are serialized and certified.
Complete Sampling Solutions
Automating the sampling process improves accuracy, reproducibility and simplifies method transfer. Standardized modules for sample withdrawal allow sampling tailored to your application. For dissolution sample withdrawal, four key factors must be considered: height reproducibility, automation potential, hydrodynamic impact and possible coupling to temperature monitoring. Automating the process with simultaneous sampling and automatic pumping improves time and volume accuracy. Based on your requirements, SOTAX dissolution baths offer a wide variety of manual and automatic sampling possibilities:
- Simple manual sample withdrawal using a glass pipette
- Stand-alone type sampling probe with additional pipette guide
- Stationary cannula in different materials and diameters for sampling with disposable syringes
- Automatic simultaneous sampling with the unique HollowShaft™ – reducing hydrodynamic perturbation
- Automatic simultaneous sampling with cannula and AutoLift™ (AT Xtend™ only) for maximum flexibility
User-friendly with EasyTouch™
Simple and intuitive touch screen operation makes test set-up and method programming easier than ever. Logical, icon-based menu structures and multi-language capability reduce analyst training times to a minimum. The large integrated 5.4″ color touch screen sets new standards for efficient operation. User rights settings, method programming, data visualization, data transfer and reporting are readily available at the touch of a button. Using the built-in USB port, methods can be conveniently exchanged between different AT installations – eliminating redundant programming tasks. Various communication ports allow local and network printing, status monitoring via TCP/IP and full system control by PC software whenever needed.